Chronic Hazard Advisory Panel (CHAP) on Phthalates
Section 108 of the Consumer Product Safety Improvement Act of 2008 (CPSIA) requires the U.S. Consumer Product Safety Commission to convene a Chronic Hazard Advisory Panel (CHAP) to study the effects on children’s health of all phthalates and phthalate alternatives as used in children’s toys and child care articles. The CHAP shall make recommendations to the Commission regarding any phthalates (or combinations of phthalates) in addition to those identified in section 108 of the CPSIA or phthalate alternatives that the panel determines should be declared banned hazardous substances. This page lists several documents that have been received by the CHAP. Presentations and reports submitted to a CHAP meeting are available at the page dedicated to that meeting.
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December 2011 Teleconference Federal Register Notice [PDF], teleconference Log [PDF], list of registrants [PDF], and Message from Cheryl Falvey, CPSC General Counsel [PDF]
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November 2011 Meeting
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September 2011 Teleconference Federal Register Notice [PDF], teleconference Log [PDF], and list of registrants [PDF]
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July 2011 Meeting
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March 2011 Meeting
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December 2010 Meeting
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November 2010 Teleconference Notice [PDF], Federal Register Notice [PDF], teleconference Log [PDF], and list of registrants [PDF]
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July 2010 Meeting
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April 2010 Meeting
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Toxicity Reviews of 1,2-benzenedicarboxylic acid, di-2-propenyl ester (diallyl phthalate), bis(2-methoxyethyl) phthalate (DMEP), and 2,2,4-trimethyl-1,3-pentanediol diisobutyrate (TXIB), February 2011 [PDF]
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Documents Received from Non-CPSC Sources
These documents were not prepared by the Commission or Commission staff and are not official documents of the CPSC, have not been reviewed by, and may not necessarily reflect the views of, the Commission.
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Transmittal Email from Steve Risotto, American Chemistry Council, September 19, 2011
- Göen et al. (2011) Trends of the internal phthalate exposure of young adults in Germany - Follow-up of a retrospective human biomonitoring study. International Journal of Hygiene and Environmental Health (in press). This article is copyrighted and therefore anyone who wants to obtain a copy can request it from the International Journal of Hygiene and Environmental Health.
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Transmittal Emails from Steve Risotto, American Chemistry Council, September 25, 2009, August 28, 2009 and April 21, 2010
- Interspecies Bioassay SOT Poster
- Concentration Database - DEHP 2009 [PDF]
- Concentration Database - Other PEs 2009 [PDF]
- Phthalate Database References 2009 [PDF]
- Phthalate Monoesters 2009 [PDF]
- Aylward LL, Hays SM, Gagné M, Krishnan K. (2009) Derivation of biomonitoring equivalents for di(2-ethylhexyl)phthalate (CAS No. 117-81-7). Regulatory Toxicology and Pharmacology 55: 249-258.
- Aylward LL, Hays SM, Gagné M, Krishnan K. (2009) Derivation of biomonitoring equivalents for di-n-butyl phthalate (DBP), benzylbutyl phthalate (BzBP), and diethyl phthalate (DEP). Regulatory Toxicology and Pharmacology 55:259-267.
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Approach to Cumulative Risk, ExxonMobil, PowerPoint Presentation, March 23, 2010 [PDF]
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Eastman Chemical Company Cover Letter, March 1, 2010 [PDF]
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Diisononyl Phthalate (DINP) Carcinogenicity Hazard Assessment, ExxonMobil Chemical Company, February 16, 2010 [PDF]
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Robust Summary for DINCH, January 6, 2010 [PDF]
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Robust Summary for DPHP, January 6, 2010 [PDF]
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Toxicity Summary for Eastman 168 Plasticizer, January 5, 2010 [PDF]
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CPSC Meeting, Non-Phthalate Ester Plasticizers Panel (PowerPoint Presentation), American Chemistry Council, December 15, 2009 [PDF]
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Plasticizers and the CPSIA, PowerPoint Presentation, ExxonMobil, July 16, 2009 [PDF]
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BASF Meeting with CPSC (PowerPoint Presentation), June 22, 2009 [PDF]
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Review of Recent Scientific Data on Di-isononyl Phthalate (DINP) and Risk Characterisation for its use in Toys and Childcare articles, European Council for Plasticisers and Intermediates, Technical Report 2009-0601-DINP, June 2009 [PDF]
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Toxicity Summary for Eastman TXIB Formulation Additive, Eastman Chemical Company, November 28, 2007 [PDF]
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Chen CY (2004) Biosynthesis of di-(2-ethylhexyl) phthalate (DEHP) and di-n-butyl phthalate (DBP) from red alga - Bangia atropurpurea. Water Research 38: 1014-1018
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Namikoshi M, Jujiwara T, Nishikawa T, Ukai K (2006) Natural abundance 14C content of dibutyl phthalate (DBP) from three marine algae. Marine Drugs 4: 290-297.
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Commercial status of other phthalates, Comments to CPSC 1-25-2011, P. Harmon, BASF [PDF]
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Miscellaneous phthalates - status of use in N. America, P. Harmon, BASF [PDF]
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REACH registered products from ECHA, Steve Risotto, American Chemistry Council [PDF]
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REACH: Substances Intended to be Registered as of 30-Nov-2010, Steve Risotto, American Chemistry Council [PDF]
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Letter [PDF] from Latham & Watkins - Request to Present New Data to the Chronic Hazard Advisory Panal (CHAP) on Phthalates, August 29, 2011 and CPSC Staff Reply [PDF], September 15, 2011
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Letter from Michael A. Kamrin, Ph.D., Michigan State University [PDF], September 28, 2011
- Kamrin, Michael A.(2009) Phthalate Risks, Phthalate Regulation, and Public Health: A Review. Journal of Toxicology and Environmental Health, Part B,12:2,157-174.
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Letter [PDF] from Steve Risotto re. Borgert, C.J., et al. The human relevant potency threshold: Reducing uncertainty by human calibration of cumulative risk
assessments. Regul. Toxicol. Pharmacol. (2011), doi:10.1016/j.yrtph.2011.10.012
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